Non Invasive Prenatal Test (NIPT) + Scan

£ 400.00 RRP
10 to 22 weeks

Available to women from 16 years of age.

This service includes a Non Invasive Prenatal Test (NIPT for short, sometimes called the Harmony™ prenatal blood test from Ariosa Diagnostics Inc or Vision™ from Future Health Biobank) and an ultrasound scan. Availability of Harmony and/or Vision varies by location. Your blood needs to be taken either by us at the time of your appointment or privately by your midwife, GP or local phlebotomist.

When you book online, depending on your chosen location you may be contacted to arrange the most convenient way for you to have this done close by.

Note that the results from your baby's DNA blood test are normally available approximately 7 working days after your appointment and we recommend that you present your results to your usual healthcare professional whose contact details we take at the time of booking. Your choice of a free rescan may be appropriate if we are unable to perform the primary purpose of this scan.

All scans are performed by a qualified Sonographer with diagnostic obstetric scanning experience.

Pregnancy Scan NIPT ultrasound scan bw image
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Primary purpose of the blood test and scan

To test for Down's syndrome and certain other genetic conditions (T18 and 13 and Turners syndrome) from a maternal blood sample.

The ultrasound scan will determine viability, if single or multiple fetus are present and accurately date your pregnancy. Very occasionally it may involve transvaginal / internal scanning.


  • 30 minute diagnostic appointment
  • A scan for viability (heartbeat) and gestation measurements
  • A maternal blood sample (from the arm) taken into 2 sample bottles
  • Ultrasound report and 2D ultrasound b/w prints in sleeve on the day, fetal DNA blood results approximately 7 working days later
  • Plus complimentary sexing if requested either with ultrasound* (from 16 weeks gestation or later) on the day or included with your blood test result (from 10 weeks)
  • Plus 4DFREEVIEW™ (from 12 weeks) with 3D ultrasound b/w prints in sleeve**
  • Ultrasound Direct toMOBILE delivery of your scan images and report
*Complimentary sexing with ultrasound
If you would like to know the sex of your baby we will give you our professional opinion with this scan free of charge. If your baby’s position is not favorable to do this on the day however, we cannot offer a free rescan for this purpose.


This scan includes viewing your baby in live 4D from available views and thermal b/w 3D scan prints at no extra charge. Please note that 4DFREEVIEW is a free option and if your baby’s position is not favorable for aesthetics on the day, we cannot offer a free rescan for this reason.
Pregnancy Scan NIPT ultrasound scan 3D colour image

Pre-scan preparation

Need to expose lower abdomen so ideally wear 2 piece garments i.e trousers or skirt and top.

Drink 0.5 Ltr (1 pint) clear fluid approx 1 hour before appointment time.

Please do not empty your bladder before the examination.

Please bring your hand held notes with you to the scan.

Guide to number of guests

Most clinics can comfortably accommodate 5 guests including children for this scan. If you would like to bring more, please contact your chosen clinic when booking to check how many we can accommodate.

Important - your personal information

The NIPT is analysed in the UK by our authorised partners, Harmony via TDL or Vision via Future Health Biobank. By booking a NIPT appointment with us you are agreeing to your personal information being shared with the relevant partners solely for the purpose of this test. Your express permission will also be asked during your appointment.

Frequently Asked Questions

NIPT with scan compared to NT scan with bloods
What are the differences between NT and NIPT?
A Nuchal Translucency (NT) measurement (the thickness of the fluid at the back of the baby's neck) with ultrasound when combined with a blood test and other maternal information, results in a risk factor or likelihood of a Down syndrome baby.

NIPT, on the other hand, directly analyses the cell-free fetal DNA circulating in the pregnant mother's blood to detect the presence (or not) of Down syndrome (trisomy 21) and other common fetal chromosomal conditions (trisomies 18 and 13). NIPT can also be used to detect Turner syndrome.

The accuracy level for NIPT is the highest available for this type of antenatal screening and is recommended by the International Society of Prenatal Diagnosis (ISPD).

As shown in the table above, NIPT can also be performed over a wider gestational age range and is less likely to give a false indication of Down syndrome (false positive rate).
Why from 10 weeks?

Cell-free fetal DNA (cff DNA) comes from the placenta.

It is first detectable from about 4-5 weeks’ gestation and reaches the required level needed to test for Down syndrome by 10 weeks’ gestation in most pregnancies.

Can I have this with a twin pregnancy?
This test is suitable for twin multiple pregnancies but not additional (i.e triplets or higher). Also, in the event of a positive result, the test can not determine which fetus is affected.
In the event that the pregnancy shows a twin demise/empty second sac (vanishing twin) we would be unable to undertake this test as it invalidates the results.
Can I have this with an IVF pregnancy?
Yes. This test is appropriate for IVF pregnancies.
Can I find out the sex of the baby from the blood test?
The blood test can accurately determine the gender of both singleton and twin pregnancies when requested and at no further charge.
Can the sex chromosomes be analysed for anomalies ?
Yes. We can undertake Sex Chromosome Aneuploidy screening on request to evaluate the X and Y chromosomes. The most common sex chromosome aneuploidies include Monosomy X (Turner Syndrome), XXY or XXYY (Klinefelter Syndrome), XXX (Triple X Syndrome or Trisomy X) and XXY. We can do this without revealing the babies sex if you do not want to know, however, if your baby tests high risk for any of these the gender will be revealed.
How long do I wait for the blood test results?
Your NIPT Harmony™ prenatal test is performed in the UK by TDL Genetics in London and the results from your baby's DNA blood test will normally be approximately 7-10 working days after your appointment.
How accurate are the results?
The test has a >99% accuracy for Downs Syndrome (Trisomy 21), 97.4% accuracy for Edwards Syndrome (Trisomy 18) and 93.8% accuracy for Patau’s Syndrome (Trisomy 13).
The NIPT is more accurate than the first trimester combined test or second trimester quadruple test for estimating the chance or the risk that the baby has Downs syndrome. 
The false positive rate for all Trisomy’s is <0.1%. Conventional screening tests can miss 15% or more of trisomy 21 cases. 
There maybe some factors which cause an inconclusive result (see further reading) and a further invasive test may be required for accurate determination.
We can assist your Healthcare professional in these circumstances.
What if my results indicate a baby with Down's Syndrome?

There are three possible results from NIPT for Down syndrome:

Predicted to be affected by Down syndrome. An invasive test is required to confirm the result.

Highly unlikely to be affected by Down syndrome.

Inconclusive results happen in up to 4% of cases. This is usually because the proportion of fetal DNA present in the sample is not high enough to give an accurate result. NIPT may be repeated with the hope that the cff DNA levels will have increased due to the increased gestation. NIPT detects around 98% of all babies with Down, Edwards and Patau syndromes.

What if the sample fails?
Statistically there is a 3 to 4% failure rate that there is not enough cell free DNA in the blood sample to analyse. In this event a new sample will need to be taken and resent at no extra cost.
What if I have a high BMI?

The relative proportion of cell-free fetal DNA is reduced in women with a high BMI as they have more of their own cell-free DNA circulating in their blood.

This may increase the chance of getting an inconclusive result.

What other conditions can be detected with NIPT?
In addition to Down syndrome (Trisomy 21), Edwards Syndrome (Trisomy 18), and Patau’s Syndrome (Trisomy 13) we are able to, on request, look at other aneuploidies linked to the sex chromosomes.
Please note that this will reveal the gender of your baby if the results are high risk. 
The most common sex chromosome aneuplodies include:
Monosomy X (Turners Syndrome) 
XXY or XXYY (Klinefelter Syndrome) 
XXX (Triple X Syndrome or Trisomy X) 

Further information – recommended reading

The following links may provide you with further, useful information regarding our NIPT with scan service:

Book your Babybond® NIPT + Scan now

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